hsa_circ_0115355 promotes pancreatic β‐cell function in patients with type 2 diabetes through the miR‐145/SIRT1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24583
Abstract: Type 2 diabetes mellitus (T2DM) is a complex metabolic disease closely related to obesity, a growing global health problem. T2DM is characterized by decreased islet beta‐cell mass and impaired insulin release from these cells, and… read more here.
Keywords: circ 0115355; cell; 0115355 promotes; hsa circ ... See more keywords
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3
Sign Up to like & getrecommendations! Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-021-02007-w
Abstract: MAP4K4 is a Ste20 member and reported to play important roles in various pathologies, including in cancer. However, the mechanism by which MAP4K4 promotes pancreatic cancer is not fully understood. It is suggested that MAP4K4… read more here.
Keywords: map4k4; pancreatic cancer; map4k4 promotes; promotes pancreatic ... See more keywords
Abstract C114: Engrailed-1 promotes pancreatic cancer metastasis
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DOI: 10.1158/1538-7445.panca2023-c114
Abstract: Engrailed-1 (EN1) is a critical homeodomain transcription factor (TF) required for neuronal survival, and EN1 expression has been shown to promote aggressive forms of triple negative breast cancer. Here, we report that EN1 is aberrantly… read more here.
Keywords: cancer; promotes pancreatic; engrailed promotes; pancreatic cancer ... See more keywords
An Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
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DOI: 10.1158/2159-8290.cd-rw2018-003
Abstract: Stress-activated ADRB2 signaling promotes tumor innervation and PDAC development. read more here.
Keywords: loop promotes; neurotrophin feedforward; adrenergic neurotrophin; promotes pancreatic ... See more keywords