MicroRNA-371a-3p promotes progression of gastric cancer by targeting TOB1.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.11.021
Abstract: An integrated study was conducted to identify the potential prognosis biomarker of the gastric cancer. The study analyzed the expression level of microRNAs (miRNAs) and clinical follow-up information of gastric cancer patients. miR-371-3p was determined… read more here.
Keywords: mir 371; 371a promotes; gastric cancer; microrna 371a ... See more keywords
RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71403-1
Abstract: Regulatory factor X-5 (RFX5) represents a key transcription regulator of MHCII gene expression in the immune system. This study aims to explore the molecular mechanisms and biological significance of RFX5. Firstly, by analyzing ENCODE chromatin… read more here.
Keywords: rfx5 promotes; kdm4a; progression hepatocellular; rfx5 ... See more keywords
IL-27Ra promotes the progression of neonatal necrotizing enterocolitis
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-26899-w
Abstract: Neonatal necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disease of premature infants, characterized by immune dysregulation and compromised intestinal barrier integrity. Interleukin-27 receptor α (IL-27Ra), a critical component of the JAK-STAT signaling pathway, exhibits dual… read more here.
Keywords: 27ra promotes; necrotizing enterocolitis; neonatal necrotizing; promotes progression ... See more keywords
LncRNA HOXA10-AS promotes the progression of esophageal carcinoma by regulating the expression of HOXA10
Sign Up to like & getrecommendations! Published in 2023 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2108633
Abstract: ABSTRACT Esophageal cancer (EC) remains a primary cause of cancer-associated fatality worldwide and is characterized by poor prognosis. HOXA10-AS is reported to be relevant with the development of different human cancers. However, its role and… read more here.
Keywords: progression esophageal; hoxa10; lncrna hoxa10; hoxa10 promotes ... See more keywords
MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2
Sign Up to like & getrecommendations! Published in 2022 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001856
Abstract: To investigate the role of miR-140/BCL2L2 axis on the formation of intracranial aneurysms. The expression of miR-140 in the serum of patients with intracranial aneurysms and healthy volunteers was detected. CCK-8 assay and Annexin V-FITC/PI… read more here.
Keywords: progression intracranial; mir 140; 140 bcl2l2; intracranial aneurysms ... See more keywords
HuR Promotes the Progression of Gastric Cancer through Mediating CDC5L Expression
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/5141927
Abstract: Methods We performed qRT-PCR, cell cycle assay, cell migration, and mouse transplantation model analysis in our experiments. It has been clarified that HuR and microRNAs (miRNAs) have important interplays in the regulation of tumor progression.… read more here.
Keywords: expression; hur promotes; promotes progression; mir 133b ... See more keywords
IFN-γ promotes the progression of iMCD by activating inflammatory monocytes.
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood.2024027689
Abstract: A deeper understanding of the immune landscape in patients with idiopathic multicentric Castleman disease (iMCD) is essential to establish early prognostic stratification and uncover novel therapeutic targets. We employed single-cell RNA sequencing (scRNA-seq) of peripheral… read more here.
Keywords: ifn promotes; progression imcd; imcd activating; ccl monocytes ... See more keywords
HMGA1 promotes the progression of lung adenocarcinoma through the STAT1-mediated transcriptional activation of DDAH1
Sign Up to like & getrecommendations! Published in 2025 at "Biology Direct"
DOI: 10.1186/s13062-025-00688-x
Abstract: Advancements in precision oncology have generated increased interest in the prognostic and therapeutic capabilities of transcription factors, among which HMGA1 is significantly correlated with LUAD prognosis. However, our understanding of HMGA1 remains insufficient. This study… read more here.
Keywords: hmga1; stat1; ddah1; hmga1 promotes ... See more keywords
IDO1 Promotes the Progression of NSCLC by Regulating the Polarization of M2 Macrophages
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s398908
Abstract: Purpose Non-small cell lung cancer (NSCLC) is currently a problem in the clinic and in society. Tumor-related macrophages (TAMs) in the tumor microenvironment (TME) play a vital role in the development of NSCLC. Patients and… read more here.
Keywords: ido1 promotes; expression; polarization; promotes progression ... See more keywords
PSMD2 promotes the progression of bladder cancer and is correlated with immune infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1058506
Abstract: Introduction PSMD2 plays an oncogenic role in multiple human malignancies, while it is still unclear that the potential roles and underlying mechanisms of PSMD2 in BCa. Methods The RNA-seq from TCGA and GTEx database was… read more here.
Keywords: bladder; psmd2 bca; bca; expression ... See more keywords
Bisphenol A Promotes the Progression of Hormone-Sensitive Breast Cancers Through Several Inflammatory Pathways
Sign Up to like & getrecommendations! Published in 2025 at "Cancers"
DOI: 10.3390/cancers17142373
Abstract: Simple Summary Bisphenol A is a monomer used to produce polymers used in the production of polycarbonate plastics and epoxy resins. It is found throughout the world and, under harsh conditions, tends to leak out… read more here.
Keywords: breast; bisphenol promotes; hormone sensitive; progression hormone ... See more keywords