Oxidation of Dueling Cysteine Promotes Subunit Exchange in SOD1.
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DOI: 10.1021/acschemneuro.3c00174
Abstract: The heterodimerization of wild-type (WT) Cu, Zn superoxide dismutase-1 (SOD1) and mutant SOD1 might be a critical step in the pathogenesis of SOD1-linked amyotrophic lateral sclerosis (ALS). Post-translational modifications that accelerate SOD1 heterodimerization remain unidentified.… read more here.
Keywords: oxidation; heterodimerization; sod1; promotes subunit ... See more keywords