Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators.
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DOI: 10.1016/j.phrs.2021.105556
Abstract: The pentacyclic triterpenoid quinone methide celastrol (CS) from Tripterygium wilfordii Hook. F. effectively ameliorates inflammation with potential as therapeutics for inflammatory diseases. However, the molecular mechanisms underlying the anti-inflammatory and inflammation-resolving features of CS are… read more here.
Keywords: anti inflammatory; specialized pro; lipid mediators; pro resolving ... See more keywords