The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022016929
Abstract: Key Points • CD53 is upregulated in HSCs in response to various inflammatory and proliferative stressors.• CD53 promotes HSC return to quiescence via promotion of the DREAM complex activity and downregulation of cycling-associated genes. read more here.
Keywords: cd53; quiescence; dream complex; via promotion ... See more keywords