The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis
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DOI: 10.1073/pnas.2200468119
Abstract: Significance Protein aggregation is a major problem for human health. However, our understanding of how folded proteins aggregate into amyloid lags behind. Using the tripartite β-lactamase assay (TPBLA) with our test protein, β2-microglobulin (β2m), we… read more here.
Keywords: aggregation; aggregation prone; effect mutation; prone protein ... See more keywords