N‐methyl‐d‐aspartate receptor dysfunction in the prefrontal cortex of stroke‐prone spontaneously hypertensive rat/Ezo as a rat model of attention deficit/hyperactivity disorder
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DOI: 10.1002/npr2.12007
Abstract: We previously reported that stroke‐prone spontaneously hypertensive rat/Ezo (SHRSP/Ezo) has high validity as an attention deficit/hyperactivity disorder (AD/HD) animal model, based on its behavioral phenotypes, such as inattention, hyperactivity, and impulsivity. Fronto‐cortical dysfunction is implicated… read more here.
Keywords: stroke prone; spontaneously hypertensive; hyperactivity; hypertensive rat ... See more keywords
Evaluation of Pathological Association between Stroke-Related QTL and Salt-Induced Renal Injury in Stroke-Prone Spontaneously Hypertensive Rat
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DOI: 10.1155/2019/5049746
Abstract: The stroke-prone spontaneously hypertensive rat (SHRSP) suffers from severe hypertension and hypertensive organ damage such as cerebral stroke and kidney injury under salt-loading. By a quantitative trait locus (QTL) analysis between SHRSP and SHR (the… read more here.
Keywords: stroke prone; spontaneously hypertensive; salt; renal injury ... See more keywords
Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function
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DOI: 10.1186/s12872-018-0768-6
Abstract: BackgroundAntioxidants have shown great promise in stroke prevention. Diarylheptanoids (also known as diphenylheptanoids) are a small class of plant secondary metabolites that possess antioxidant activity greater than that of α-tocopherol. Curcumin is the best known… read more here.
Keywords: endothelial function; spontaneously hypertensive; vascular endothelial; prone spontaneously ... See more keywords
Gut-Microbiota Dysbiosis in Stroke-Prone Spontaneously Hypertensive Rats with Diet-Induced Steatohepatitis
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DOI: 10.3390/ijms24054603
Abstract: Metabolic-dysfunction-associated fatty-liver disease (MAFLD) is the principal worldwide cause of liver disease. Individuals with nonalcoholic steatohepatitis (NASH) have a higher prevalence of small-intestinal bacterial overgrowth (SIBO). We examined gut-microbiota isolated from 12-week-old stroke-prone spontaneously hypertensive-5… read more here.
Keywords: gut microbiota; stroke prone; shrsp5 rats; prone spontaneously ... See more keywords