CXCR4 expression is associated with proneural‐to‐mesenchymal transition in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34329
Abstract: Glioblastoma (GBM) is the most common primary intracranial malignant tumor and consists of three molecular subtypes: proneural (PN), mesenchymal (MES) and classical (CL). Transition between PN to MES subtypes (PMT) is the glioma analog of… read more here.
Keywords: cxcr4 expression; mesenchymal transition; proneural mesenchymal; expression ... See more keywords
ME2 Promotes Proneural–Mesenchymal Transition and Lipogenesis in Glioblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.715593
Abstract: Malic enzyme 2 (ME2) catalyzes the formation of pyruvate from malic acid and is abnormally expressed in some tumors. However, the exact effects of ME2 on proneural–mesenchymal transition (PMT) and lipogenesis in glioblastoma multiforme (GBM)… read more here.
Keywords: mesenchymal transition; me2; lipogenesis glioblastoma; gbm ... See more keywords
Heterogeneity of Amino Acid Profiles of Proneural and Mesenchymal Brain-Tumor Initiating Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043199
Abstract: Glioblastomas are highly malignant brain tumors that derive from brain-tumor-initiating cells (BTICs) and can be subdivided into several molecular subtypes. Metformin is an antidiabetic drug currently under investigation as a potential antineoplastic agent. The effects… read more here.
Keywords: brain tumor; acid profiles; proneural mesenchymal; amino acid ... See more keywords