Proof-Reading Thioesterase Boosts Activity of Engineered Nonribosomal Peptide Synthetase
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DOI: 10.1021/acschembio.2c00341
Abstract: Nonribosomal peptide synthetases (NRPSs) are a vast source of valuable natural products, and re-engineering them is an attractive path toward structurally diversified active compounds. NRPS engineering often requires heterologous expression, which is hindered by the… read more here.
Keywords: thioesterase boosts; proof reading; reading thioesterase; peptide ... See more keywords