Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice.
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DOI: 10.1016/j.chembiol.2018.01.007
Abstract: Superoxide radical anion (O2⋅‒) and other reactive oxygen species are constantly produced during respiration. In mitochondria, the dismutation of O2⋅‒ is accelerated by the mitochondrial superoxide dismutase 2 (SOD2), an enzyme that has been traditionally associated… read more here.
Keywords: peroxidase; prooxidant peroxidase; mitochondrial superoxide; superoxide dismutase ... See more keywords