Role of PROP1 in postnatal pituitary gland maturation.
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DOI: 10.1210/endocr/bqaf047
Abstract: Mutations in the pituitary-specific transcription factor PROP1 are the most common, known cause of hypopituitarism in humans. Prop1 is the first pituitary-specific gene in the hierarchy of transcription factors that regulate pituitary development. It is… read more here.
Keywords: prop1; role; stem cells; postnatal pituitary ... See more keywords
7704 Generating pituitary cells from iPSCs of patients with child onset congenital hypopituitarism harboring PROP1 pathogenic allelic variants
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvae163.1219
Abstract: Abstract Disclosure: J.M. Marques: None. F. Fattahi: None. L.R. Carvalho: None. Introduction: Reduced or absent levels of pituitary hormones due to genetic or organic causes is known as combined pituitary hormone deficiency (CPHD) and PROP1… read more here.
Keywords: prop1; pituitary cells; cells ipscs; 7704 generating ... See more keywords