Effect of Rythmol (propafenone HCl) administration during pregnancy in Wistar rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23085
Abstract: Propafenone is a well‐known Class 1C antiarrhythmic agent that has sodium channel blocking properties as well as the ability to block 13 other channels and a modest calcium antagonistic effect. Propafenone has a profound electrophysiologic… read more here.
Keywords: effect; effect rythmol; rythmol propafenone; propafenone ... See more keywords
A 35-year effective treatment of catecholaminergic polymorphic ventricular tachycardia with propafenone
Sign Up to like & getrecommendations! Published in 2019 at "HeartRhythm Case Reports"
DOI: 10.1016/j.hrcr.2018.04.003
Abstract: Key Teaching Points • Despite proven catecholaminergic polymorphic ventricular tachycardia (CPVT) with pathogen RyR2 mutation and recurrent syncope, patients could have a favorable long-term outcome over 35 years under treatment. • Propafenone could be effective… read more here.
Keywords: ventricular tachycardia; effective treatment; polymorphic ventricular; treatment ... See more keywords
A new sensing platform based on NH2fMWCNTs for the determination of antiarrhythmic drug Propafenone in pharmaceutical dosage forms.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.06.026
Abstract: A novel sensor based on a modification of glassy carbon electrode (GCE) with NH2-functionalized multi-walled carbon nano-tubes (NH2fMWCNTs) is reported and its applicability to the electrochemical sensing of Propafenone (PPF) demonstrated. The electrochemical catalytic activity… read more here.
Keywords: sensor; new sensing; platform based; dosage ... See more keywords
P1907Propensity score matched analysis of antazoline mesylate vs. amiodarone or propafenone for pharmacological cardioversion of short-duration atrial fibrillation
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz748.0654
Abstract: Former studies corroborated promising quinidine-like properties of antazoline mesylate facilitating rapid cardioversion atrial fibrillation (AF). Still, paucity of data exists concerning direct comparison of antazoline to other antiarrhythmic agents. The study aimed to verify the… read more here.
Keywords: propafenone; amiodarone propafenone; pharmacological cardioversion; antazoline ... See more keywords
Influence of CYP2D6 genetic variation on adverse events with propafenone in the pediatric and young adult population
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DOI: 10.1111/cts.13296
Abstract: Propafenone is an antiarrhythmic drug metabolized primarily by cytochrome P450 2D6 (CYP2D6). In adults, propafenone adverse events (AEs) are associated with CYP2D6 poor metabolizer status; however, pediatric data are lacking. Subjects were tested for 10… read more here.
Keywords: genetic variation; cyp2d6 genetic; cyp2d6; propafenone ... See more keywords
Evaluation of Index of Cardio-Electrophysiological Balance in Patients With Atrial Fibrillation on Antiarrhythmic-Drug Therapy
Sign Up to like & getrecommendations! Published in 2021 at "cardiology research"
DOI: 10.14740/cr.v12i1.1185
Abstract: Background: Index of cardio-electrophysiological balance (iCEB) has been described as a novel risk marker for predicting malignant ventricular arrhythmia. There remains limited evidence on the effects of amiodarone and propafenone used for sinus rhythm maintenance… read more here.
Keywords: drug therapy; propafenone; antiarrhythmic drug; index cardio ... See more keywords
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study .
Sign Up to like & getrecommendations! Published in 2018 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp203181
Abstract: Propafenone is an antiarrhythmic drug applied to ventricular arrhythmias, initially recognized as a sodium channel blocker. This study aims to evaluate the bioequivalence of two propafenone formulations (300 mg tablet) in healthy subjects under non-fasting conditions.… read more here.
Keywords: bioequivalence; study; liquid chromatography; propafenone ... See more keywords