Propagation of Tau Pathology: Integrating Insights From Postmortem and In Vivo Studies
Sign Up to like & getrecommendations! Published in 2020 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2019.09.019
Abstract: Cellular accumulation of aggregated forms of the protein tau is a defining feature of so-called tauopathies such as Alzheimer's disease, progressive supranuclear palsy, and chronic traumatic encephalopathy. A growing body of literature suggests that conformational… read more here.
Keywords: tau pathology; pathology; postmortem; pathology integrating ... See more keywords
Propagation of Tau aggregates
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Brain"
DOI: 10.1186/s13041-017-0298-7
Abstract: Since 2009, evidence has accumulated to suggest that Tau aggregates form first in a small number of brain cells, from where they propagate to other regions, resulting in neurodegeneration and disease. Propagation of Tau aggregates… read more here.
Keywords: seed; tau; tau aggregates; brain ... See more keywords