Highly regioselective 1,3-dipolar cycloaddition of 3′-O-propargyl guanosine with nitrile oxide: An efficient method for the synthesis of guanosine containing isoxazole moiety
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DOI: 10.1016/j.tetlet.2020.152464
Abstract: The 1,3-dipolar cycloaddition reaction of 3′-O-propargyl guanosine with various in-situ generated nitrile oxides in the presence of DMF as a solvent is described. It is noteworthy that the reaction is highly regioselective that affords biologically… read more here.
Keywords: guanosine containing; guanosine; propargyl guanosine; containing isoxazole ... See more keywords