Catalytic Enantioselective Carbonyl Propargylation Beyond Preformed Carbanions: Reductive Coupling and Hydrogen Auto‐Transfer
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DOI: 10.1002/cctc.201801121
Abstract: Chiral metal complexes catalyze enantioselective carbonyl propargylation via reductive coupling or as hydrogen auto‐transfer processes, in which reactant alcohols serve dually as reductant and carbonyl proelectrophile. Unlike classical propargylation protocols, which rely on allenylmetal reagents… read more here.
Keywords: carbonyl propargylation; propargylation; enantioselective carbonyl; coupling hydrogen ... See more keywords
Synthesis and characterization of nano−zinc wire using a self designed unit galvanic cell in aqueous medium and its reactivity in propargylation of aldehydes
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.07.012
Abstract: Abstract Electrochemistry is used for propargylation of carbonyls in aqueous ZnCl2 medium. For electrochemical process we designed a unit galvanic cell. ZnCl2 is used as stoichiometric reagent and causes electrochemical deposition of zinc in cathode.… read more here.
Keywords: nano zinc; designed unit; galvanic cell; zinc ... See more keywords
Reactions of alkyl 4-hydroxybut-2-ynoates with arenes under superelectrophilic activation with triflic acid or HUSY zeolite: Alternative propargylation or allenylation of arenes, and synthesis of furan-2-ones
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130517
Abstract: Abstract Reactions of alkyl 4-aryl(or 4,4-diaryl)-4-hydroxybut-2-ynoates [Ar(H or Ar')(OH)C4–C3≡C2–CO2Alk] with arenes under the action of triflic acid TfOH or HUSY zeolite result in the formation of two main compounds, aryl substituted furan-2-ones or products of… read more here.
Keywords: triflic acid; husy zeolite; furan ones; hydroxybut ynoates ... See more keywords
Propargylation of Ugi Amide Dianion: An Entry into Pyrrolidinone and Benzoindolizidine Alkaloid Analogues.
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DOI: 10.1021/acs.orglett.8b00687
Abstract: Propargylation of Ugi adducts under the addition of excess sodium hydride in DMSO leads to direct formation of pyrrolidinone enamides, which are useful precursors of iminium intermediates and may be trapped by various nucleophiles. This… read more here.
Keywords: propargylation; pyrrolidinone; benzoindolizidine; propargylation ugi ... See more keywords
One-Pot Assembly of 3-Hydroxycarbazoles via Uninterrupted Propargylation/Hydroxylative Benzannulation Reactions.
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DOI: 10.1021/acs.orglett.9b04472
Abstract: A novel strategy for the synthesis of 3-hydroxycarbazoles involving the consecutive propargylation/palladium-catalyzed hydroxylative benzannulation of indole-2-carbonyls with propargylic alcohols has been exploited. This one-pot procedure leads to a wide range of substituted 3-hydroxycarbazoles in high… read more here.
Keywords: pot assembly; hydroxylative benzannulation; propargylation; one pot ... See more keywords