Efficient and stereoselective synthesis of (S)-α-propargylglycine derivatives from allenylboronic acid
Sign Up to like & getrecommendations! Published in 2019 at "Mendeleev Communications"
DOI: 10.1016/j.mencom.2019.09.006
Abstract: The Petasis–Mannich reaction of allenylboronic acid with glyoxylic acid and (S)-1-phenylethylamine diastereoselectively leads to N-substituted propargylglycine of high optical purity in good yield. This product can be further subjected to esterification followed by bioconjugate synthesis… read more here.
Keywords: allenylboronic acid; propargylglycine; stereoselective synthesis; synthesis propargylglycine ... See more keywords
Asymmetric synthesis, biological activity and molecular docking studies of some unsaturated α-amino acids, derivatives of glycine, allylglycine and propargylglycine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.127850
Abstract: Abstract New enantiomerically enriched unsaturated tailor-made amino acids have been obtained. As a starting amino acid synthon for the asymmetric synthesis of tailor-made unsaturated amino acids, Ni(II) square-planar complexes of Schiff’s bases of propargylglycine, allylglycine… read more here.
Keywords: unsaturated amino; amino acids; propargylglycine; asymmetric synthesis ... See more keywords