Effect of Propargylic Substituents on Enantioselectivity and Reactivity in Ruthenium-Catalyzed Propargylic Substitution Reactions: A DFT Study
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DOI: 10.1021/acsomega.2c04645
Abstract: We recently proposed a transition-state model for asymmetric propargylic substitution reactions of propargylic alcohols catalyzed by optically active thiolate-bridged diruthenium complexes [Chem. – Asian J.2021, 16, 3760−376634549529]. In the present study, we further examined the… read more here.
Keywords: enantioselectivity; substitution; propargylic substitution; group ... See more keywords
Catalytic Asymmetric Vinylogous and Bisvinylogous Propargylic Substitution.
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DOI: 10.1021/jacs.2c06560
Abstract: Distinct regio- and enantioselectivity control in copper-catalyzed vinylogous and bisvinylogous propargylic substitution has been accomplished by using a novel chiral N,N,P ligand. The developed method provides an efficient and selective approach to an array of… read more here.
Keywords: propargylic substitution; bisvinylogous propargylic; catalytic asymmetric; vinylogous bisvinylogous ... See more keywords