β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells
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DOI: 10.1016/j.cub.2021.01.081
Abstract: Mutations in WDR45 and WDR45B cause the human neurological diseases β-propeller protein-associated neurodegeneration (BPAN) and intellectual disability (ID), respectively. WDR45 and WDR45B, along with WIPI1 and WIPI2, belong to a WD40 repeat-containing phosphatidylinositol-3-phosphate (PI(3)P)-binding protein… read more here.
Keywords: autophagosome maturation; proteins wdr45; wdr45 45b; wdr45 wdr45b ... See more keywords
Computational design of symmetrical eight-bladed β-propeller proteins
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DOI: 10.1107/s205225251801480x
Abstract: Two artificial β-propeller proteins with eight identical blades were designed, purified and crystallized. X-ray crystallography confirmed the perfectly symmetrical structures of these highly stable proteins. read more here.
Keywords: propeller proteins; propeller; eight bladed; symmetrical eight ... See more keywords