Otoferlin Is Required for Proper Synapse Maturation and for Maintenance of Inner and Outer Hair Cells in Mouse Models for DFNB9
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DOI: 10.3389/fncel.2021.677543
Abstract: Deficiency of otoferlin causes profound prelingual deafness in humans and animal models. Here, we closely analyzed developmental deficits and degenerative mechanisms in Otof knock-out (Otof–/–) mice over the course of 48 weeks. We found otoferlin… read more here.
Keywords: required proper; outer hair; proper synapse; otoferlin required ... See more keywords