Articles with "properdin binding" as a keyword



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Initial properdin binding contributes to alternative pathway activation at the surface of viable and necrotic cells

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Published in 2022 at "European Journal of Immunology"

DOI: 10.1002/eji.202149259

Abstract: Properdin, the only known positive regulator of the complement system, stabilizes the C3 convertase, thereby increasing its half‐life. In contrast to most other complement factors, properdin is mainly produced extrahepatically by myeloid cells. Recent data… read more here.

Keywords: properdin binding; alternative pathway; necrotic cells; properdin ... See more keywords