Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1
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DOI: 10.3390/molecules26051227
Abstract: The deubiquitinating enzyme (DUB) UCHL1 is implicated in various disease states including neurodegenerative disease and cancer. However, there is a lack of quality probe molecules to gain a better understanding on UCHL1 biology. To this… read more here.
Keywords: optimization anti; properties fluoromethylketones; fluoromethylketones covalent; cancer properties ... See more keywords