Key Physicochemical Characteristics Influencing ADME Properties of Therapeutic Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-7709-9_6
Abstract: Therapeutic proteins are a rapidly growing class of drugs in clinical settings. The pharmacokinetics (PK) of therapeutic proteins relies on their absorption, distribution, metabolism, and excretion (ADME) properties. Moreover, the ADME properties of therapeutic proteins… read more here.
Keywords: therapeutic proteins; key physicochemical; adme properties; properties therapeutic ... See more keywords
Plant-Made Antibodies: Properties and Therapeutic Applications.
Sign Up to like & getrecommendations! Published in 2019 at "Current medicinal chemistry"
DOI: 10.2174/0929867325666171212093257
Abstract: BACKGROUND A cost-effective plant platform for therapeutic monoclonal antibody production is both flexible and scalable. Plant cells have mechanisms for protein synthesis and posttranslational modification, including glycosylation, similar to those in animal cells. However, plants… read more here.
Keywords: antibodies properties; animal cells; plant; properties therapeutic ... See more keywords