Balanced spatiotemporal arrangements of histone H3 and H4 posttranslational modifications are necessary for meiotic prophase I chromosome organization
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31201
Abstract: Dynamic nuclear architecture and chromatin organizations are the key features of the mid‐prophase I in mammalian meiosis. The chromatin undergoes major changes, including meiosis‐specific spatiotemporal arrangements and remodeling, the establishment of chromatin loop–axis structure, pairing,… read more here.
Keywords: prophase; spatiotemporal arrangements; meiotic prophase; chromatin ... See more keywords
Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-54161-w
Abstract: In mammals, oocytes are arrested in prophase of meiosis I for long periods of time. Prophase arrest is critical for reproduction because it allows oocytes to grow to their full size to support meiotic maturation… read more here.
Keywords: prophase arrest; two mechanisms; prophase; cyclin translation ... See more keywords
Translational repression by 4E-T is crucial to maintain the prophase-I arrest in vertebrate oocytes
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62971-9
Abstract: Meiotic maturation of vertebrate oocytes occurs in the near-absence of transcription. Thus, female fertility relies on timely translational activation of maternal transcripts stockpiled in full-grown prophase-I-arrested oocytes. However, how expression of these mRNAs is suppressed… read more here.
Keywords: prophase; prophase arrest; repression; maintain prophase ... See more keywords
The proteome of developing barley anthers during meiotic prophase I.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of experimental botany"
DOI: 10.1093/jxb/erab494
Abstract: Flowering plants reproduce sexually by combining a haploid male and female gametophyte during fertilization. Male gametophytes are localized in the anthers, each containing reproductive (meiocyte) and non-reproductive tissue necessary for anther development and maturation. Meiosis,… read more here.
Keywords: barley; barley anthers; meiotic prophase; prophase ... See more keywords
Regulation of Meiotic Prophase One in Mammalian Oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.667306
Abstract: In female mammals, meiotic prophase one begins during fetal development. Oocytes transition through the prophase one substages consisting of leptotene, zygotene, and pachytene, and are finally arrested at the diplotene substage, for months in mice… read more here.
Keywords: one mammalian; meiotic prophase; prophase; regulation meiotic ... See more keywords