Recent advancements in single dose slow-release devices for prophylactic vaccines.
Sign Up to like & getrecommendations! Published in 2022 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1832
Abstract: Single dose slow-release vaccines herald a new era in vaccine administration. An ideal device for slow-release vaccine delivery would be minimally invasive and self-administered, making these approaches an attractive alternative for mass vaccination programs, particularly… read more here.
Keywords: single dose; dose slow; release; slow release ... See more keywords
Explanations for the high potency of HPV prophylactic vaccines
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.12.079
Abstract: HPV L1 virus-like particle (VLP) vaccines administered in a prime/boost series of three injections over six months have demonstrated remarkable prophylactic efficacy in clinical trials and effectiveness in national immunization programs with high rates of… read more here.
Keywords: potency; explanations high; prophylactic vaccines; potency hpv ... See more keywords
Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines
Sign Up to like & getrecommendations! Published in 2017 at "NPJ Vaccines"
DOI: 10.1038/s41541-017-0032-6
Abstract: AbstractmRNA represents a promising new vaccine technology platform with high flexibility in regard to development and production. Here, we demonstrate that vaccines based on sequence optimized, chemically unmodified mRNA formulated in optimized lipid nanoparticles (LNPs)… read more here.
Keywords: immune; prophylactic vaccines; vaccine technology; technology ... See more keywords
Toxicologic Pathology Forum: Tissue Evaluation in Nonclinical Toxicity Studies for Prophylactic Vaccines.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicologic pathology"
DOI: 10.1177/01926233231163474
Abstract: Nonclinical toxicity testing (GLP) of prophylactic vaccines to support human clinical trials is outlined in the World Health Organization nonclinical vaccine-development guidelines, which are followed by most regulatory agencies globally. Vaccine GLP toxicity studies include… read more here.
Keywords: toxicity studies; evaluation; nonclinical toxicity; toxicity ... See more keywords