Prenatal propofol exposure downregulates NMDA receptor expression and causes cognitive and emotional disorders in rats
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DOI: 10.1016/j.ejphar.2018.11.032
Abstract: ABSTRACT The impacts of prenatal propofol on cognition and emotion of offspring remain elusive. In the present study, pregnant rats in the second trimester were anesthetized with propofol. Neuronal apoptosis and proliferation was determined in… read more here.
Keywords: nmda receptor; exposure; prenatal propofol; expression ... See more keywords
Propofol Exposure in Early Life Induced Developmental Impairments in the Mouse Cerebellum
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00373
Abstract: Propofol is a widely used anesthetic in the clinic while several studies have demonstrated that propofol exposure may cause neurotoxicity in the developing brain. However, the effects of early propofol exposure on cerebellar development are… read more here.
Keywords: bergmann glia; propofol; exposure early; propofol exposure ... See more keywords