Multi‐threshold proportional hazards model and subgroup identification
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9589
Abstract: We propose a novel two‐stage procedure for change point detection and parameter estimation in a multi‐threshold proportional hazards model. In the first stage, we estimate the number of thresholds by formulating the threshold detection problem… read more here.
Keywords: hazards model; proportional hazards; multi threshold; subgroup identification ... See more keywords
A flexible class of generalized joint frailty models for the analysis of survival endpoints
Sign Up to like & getrecommendations! Published in 2023 at "Statistics in Medicine"
DOI: 10.1002/sim.9667
Abstract: This article focuses on shared frailty models for correlated failure times, as well as joint frailty models for the simultaneous analysis of recurrent events (eg, appearance of new cancerous lesions or hospital readmissions) and a… read more here.
Keywords: joint frailty; function; proportional hazards; analysis ... See more keywords
A double-Cox model for non-proportional hazards survival analysis with frailty.
Sign Up to like & getrecommendations! Published in 2023 at "Statistics in medicine"
DOI: 10.1002/sim.9760
Abstract: The Cox regression, a semi-parametric method of survival analysis, is extremely popular in biomedical applications. The proportional hazards assumption is a key requirement in the Cox model. To accommodate non-proportional hazards, we propose to parameterize… read more here.
Keywords: proportional hazards; cox; double cox; cox model ... See more keywords
Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3551-6
Abstract: We took an interest to read the article “Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma” conducted by Altan and colleagues that was published in Cancer Chemotherapy And Pharmacology recently [1].… read more here.
Keywords: chemotherapy; pharmacology; pancreatic ductal; ductal adenocarcinoma ... See more keywords
Hybrid L1/2 + 2 method for gene selection in the Cox proportional hazards model
Sign Up to like & getrecommendations! Published in 2018 at "Computer methods and programs in biomedicine"
DOI: 10.1016/j.cmpb.2018.06.004
Abstract: BACKGROUND AND OBJECTIVE An important issue in genomic research is to identify the significant genes that related to survival from tens of thousands of genes. Although Cox proportional hazards model is a conventional survival analysis… read more here.
Keywords: gene selection; hazards model; method; cox proportional ... See more keywords
Marginal distribution test for checking proportional hazards model assumption
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Statistical Planning and Inference"
DOI: 10.1016/j.jspi.2018.11.004
Abstract: Abstract Let Z be the covariate vector and Y be the response variable with the joint cumulative distribution function F Y , Z . Given a random sample from F Y , Z , in… read more here.
Keywords: hazards model; test; proportional hazards; marginal distribution ... See more keywords
Beyond the Hazard Ratio: Generating Expected Durations from the Cox Proportional Hazards Model
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Political Science"
DOI: 10.1017/s000712341700045x
Abstract: The Cox proportional hazards model is a commonly used method for duration analysis in political science. Typical quantities of interest used to communicate results come from the hazard function (for example, hazard ratios or percentage… read more here.
Keywords: hazards model; duration; cox proportional; expected durations ... See more keywords
Clinical effectiveness reporting of novel cancer drugs in the context of non-proportional hazards: a review of nice single technology appraisals
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462323000119
Abstract: Abstract Objectives The hazard ratio (HR) is a commonly used summary statistic when comparing time to event (TTE) data between trial arms, but assumes the presence of proportional hazards (PH). Non-proportional hazards (NPH) are increasingly… read more here.
Keywords: proportional hazards; methodology; novel cancer; clinical effectiveness ... See more keywords
Bayesian estimation of a proportional hazards model for double-censored durations
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Statistical Computation and Simulation"
DOI: 10.1080/00949655.2016.1217535
Abstract: ABSTRACT Double-censored data consist of uncensored, left- and right-censored observations and occur in survival time analysis. In this paper, parametric Bayes estimation is investigated for a proportional hazards model with durations subject to double-censoring. We… read more here.
Keywords: hazards model; double censored; model; bayesian estimation ... See more keywords
Piecewise proportional hazards models with interval-censored data
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Statistical Computation and Simulation"
DOI: 10.1080/00949655.2017.1380645
Abstract: ABSTRACT We consider the piecewise proportional hazards (PWPH) model with interval-censored (IC) relapse times under the distribution-free set-up. The partial likelihood approach is not applicable for IC data, and the generalized likelihood approach has not… read more here.
Keywords: pwph model; interval censored; likelihood; piecewise proportional ... See more keywords
Survival Analysis with Parametric Proportional Hazards Model of Random Censorship
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Mathematical and Management Sciences"
DOI: 10.1080/01966324.2016.1274929
Abstract: SYNOPTIC ABSTRACT This article presents the survival analysis in a proportional hazards model of random censorship using Weibull distribution. It is well known for Weibull distribution that the conjugate prior of the scale and shape… read more here.
Keywords: analysis; hazards model; random censorship; model random ... See more keywords