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   Articles with "prosaas" as a keyword



ProSAAS‐derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine

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recommendations! Published in 2017 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14209

Abstract: To identify neuropeptides that are regulated by cocaine, we used a quantitative peptidomic technique to examine the relative levels of neuropeptides in several regions of mouse brain following daily intraperitoneal administration of 10 mg/kg cocaine… read more here.

Keywords: prosaas; prosaas derived; regulated cocaine; cocaine ... See more keywords

The neuronal chaperone proSAAS is highly expressed in the retina

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recommendations! Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0321867

Abstract: The many layers of the neuroretina contain a complex, interconnected network of specialized neurons that both process visual stimuli and conduct processed information to higher brain areas. Neural networks rely on proteostatic control mechanisms to… read more here.

Keywords: neuronal chaperone; mouse retinal; chaperone prosaas; chaperone ... See more keywords

The proSAAS Chaperone Provides Neuroprotection and Attenuates Transsynaptic α-Synuclein Spread in Rodent Models of Parkinson's Disease.

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recommendations! Published in 2022 at "Journal of Parkinson's disease"

DOI: 10.3233/jpd-213053

Abstract: BACKGROUND Parkinson's disease involves aberrant aggregation of the synaptic protein alpha-synuclein (aSyn) in the nigrostriatal tract. We have previously shown that proSAAS, a small neuronal chaperone, blocks aSyn-induced dopaminergic cytotoxicity in primary nigral cultures. OBJECTIVE… read more here.

Keywords: prosaas; models parkinson; chaperone; parkinson disease ... See more keywords

ProSAAS peptide of the granin protein family in biochemical diagnostics of pheochromocytoma.

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recommendations! Published in 2022 at "Endokrynologia Polska"

DOI: 10.5603/ep.a2022.0017

Abstract: INTRODUCTION Pheochromocytoma is a hormonally active tumour originating from neuroendocrine cells of the adrenal medulla. Chromogranin A (CgA) and peptide proSAAS belong to the family of granins and are present in neuroendocrine cells of adrenal… read more here.

Keywords: biochemical diagnostics; family; prosaas; diagnostics pheochromocytoma ... See more keywords