Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers
Sign Up to like & getrecommendations! Published in 2019 at "Neurology"
DOI: 10.1212/wnl.0000000000008359
Abstract: Objective To define the natural history of the C9orf72 amyotrophic lateral sclerosis (C9ALS) patient population, develop disease biomarkers, and characterize patient pathologies. Methods We prospectively collected clinical and demographic data from 116 symptomatic C9ALS and… read more here.
Keywords: history study; c9orf72; natural history; history ... See more keywords
Editors' Note: Prospective Natural History Study in 24 Adult Patients With LGMDR12 Over 2 Years of Follow-up: Quantitative MRI and Clinical Outcome Measures
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000206870
Abstract: De Wel et al. prospectively studied 24 patients with autosomal recessive limb-girdle muscular dystrophy type 12 (LGMDR12). Patients with LGMDR12 had no appreciable clinical worsening over a 2-year period according to repeated standardized clinical assessments,… read more here.
Keywords: natural history; time; prospective natural; editors note ... See more keywords
Reader Response: Prospective Natural History Study in 24 Adult Patients With LGMDR12 Over 2 Years of Follow-up: Quantitative MRI and Clinical Outcome Measures
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000206871
Abstract: De Wel et al. conducted a prospective study to evaluate prognosis in 24 patients with limb-girdle muscular dystrophy autosomal recessive type 12 (LGMDR12).1 They prepared 24 healthy controls by way of an age- and sex-matching… read more here.
Keywords: natural history; prospective natural; history study; reader response ... See more keywords
Dietary Polyphenols as Prospective Natural-Compound Depression Treatment from the Perspective of Intestinal Microbiota Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27217637
Abstract: The broad beneficial effects of dietary polyphenols on human health have been confirmed. Current studies have shown that dietary polyphenols are important for maintaining the homeostasis of the intestinal microenvironment. Moreover, the corresponding metabolites of… read more here.
Keywords: prospective natural; intestinal microbiota; microbiota; depression ... See more keywords