Synthesis of 5‐ and 7‐hydroxy indolizidin‐2‐one prostaglandin‐F2α modulators and activity on myometrial contractility towards development of agents for delaying preterm birth
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DOI: 10.1002/psc.3455
Abstract: In pursuit of more effective‐labor delaying tocolytic agents, the prostaglandin F2α (PGF2α) receptor (FP) modulator PDC113.824 [(6S)‐2] represents a potent lead for developing therapy to treat preterm birth. Derivatives of FP modulator (6S)‐2 were synthesized,… read more here.
Keywords: preterm birth; hydroxy indolizidin; prostaglandin modulators; indolizidin one ... See more keywords