Ferroptosis Inhibitors Suppress Prostaglandin Synthesis in Lipopolysaccharide-Stimulated Macrophages.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00869
Abstract: Necrostatin-1 blocks ferroptosis via an unknown mechanism and necroptosis through inhibition of receptor-interacting protein kinase-1 (RIP1). We report that necrostatin-1 suppresses cyclooxygenase-2-dependent prostaglandin biosynthesis in lipopolysaccharide-treated RAW264.7 macrophages (IC50 ∼ 100 μM). This activity is… read more here.
Keywords: prostaglandin synthesis; ferroptosis; activity; ferroptosis inhibitors ... See more keywords
Corrigendum: Lipid Bodies as Sites of Prostaglandin E2 Synthesis During Chagas Disease: Impact in the Parasite Escape Mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.01168
Abstract: [This corrects the article on p. 499 in vol. 9, PMID: 29616011.]. read more here.
Keywords: corrigendum lipid; prostaglandin synthesis; synthesis chagas; lipid bodies ... See more keywords