The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP‐C1 prostate cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22776
Abstract: Corosolic acid (CRA) is found in various plants and has been used as a health food supplement worldwide. Although it has been reported that CRA exhibits significant anticancer activity, the effect of this compound on… read more here.
Keywords: prostate; corosolic acid; prostate cells; tramp ... See more keywords
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109625
Abstract: SUMMARY The normal androgen receptor (AR) cistrome and transcriptional program are fundamentally altered in prostate cancer (PCa). Here, we profile the chromatin landscape and AR-directed transcriptional program in normal prostate cells and show the impact… read more here.
Keywords: prostate; prostate cells; androgen; normal prostate ... See more keywords