Articles with "prostate epithelial" as a keyword



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Novel Human Prostate Epithelial Cell Cultures.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-22254-3_7

Abstract: Prostate cancer is the most common male cancer in the USA and the second leading cause of male cancer death in the USA. African American men have higher incidence and mortality rate from prostate cancer… read more here.

Keywords: prostate; prostate cancer; prostate epithelial; cancer ... See more keywords
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The Roles of ZnT1 and ZnT4 in Glucose-Stimulated Zinc Secretion in Prostate Epithelial Cells

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Published in 2020 at "Molecular Imaging and Biology"

DOI: 10.1007/s11307-020-01557-x

Abstract: Purpose We have previously demonstrated by MRI that high glucose stimulates efflux of zinc ions from the prostate. To our knowledge, this phenomena had not been reported previously and the mechanism remains unknown. Here, we… read more here.

Keywords: epithelial cells; storage; zinc; glucose ... See more keywords
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Castration-induced stromal remodeling disrupts the reconstituted prostate epithelial structure

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Published in 2019 at "Laboratory Investigation"

DOI: 10.1038/s41374-019-0352-4

Abstract: The normal prostate epithelial structure is maintained by homeostatic interactions with smooth muscle cells. However, structural alterations of the stroma are commonly observed in prostatic proliferative diseases, leading to the abnormalities of prostate epithelial structure.… read more here.

Keywords: stromal remodeling; epithelial structure; prostate epithelial; structure ... See more keywords
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Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase

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Published in 2020 at "Prostate Cancer and Prostatic Diseases"

DOI: 10.1038/s41391-020-00274-4

Abstract: Background Immortalization of primary prostate epithelial cells (PrEC) with just hTERT expression is particularly inefficient in the absence of DNA tumor viral proteins or p16 INK4A knockdown. Materials and methods Here, we describe the establishment… read more here.

Keywords: prostate; primary prostate; cell; expression ... See more keywords
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Influence of Trichomonas vaginalis macrophage migration inhibitory factor on the proliferation activity of prostate epithelial cell line and its preliminary mechanism

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Published in 2022 at "Andrologia"

DOI: 10.1111/and.14397

Abstract: Currently, the pathogenesis of prostate diseases is still under investigation, but it is generally clinically recognized to be related to the imbalance of prostate cell viability. Trichomonas vaginalis macrophage migration inhibitory factor (TvMIF) has been… read more here.

Keywords: cell; proliferation; vaginalis macrophage; prostate epithelial ... See more keywords
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Three‐dimensional architecture of common benign and precancerous prostate epithelial lesions

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Published in 2019 at "Histopathology"

DOI: 10.1111/his.13848

Abstract: Many glandular lesions can mimic prostate cancer microscopically, including atrophic glands, adenosis and prostatic intraepithelial neoplasia. While the characteristic histopathological and immunohistochemical features of these lesions have been well established, little is known about their… read more here.

Keywords: three dimensional; prostate; epithelial lesions; dimensional architecture ... See more keywords
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Cytotoxic Action of Palladium-Based Compound on Prostate Stem Cells, Primary Prostate Epithelial Cells, Prostate Epithelial Cells, and Prostate Cell Lines

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Published in 2022 at "Journal of Healthcare Engineering"

DOI: 10.1155/2022/4993405

Abstract: Objective Prostate cancer is one of the most common types of cancer found to occur in males and is ranked as the second-highest cause of cancer-associated deaths among male patients. In this study, we have… read more here.

Keywords: cell; prostate epithelial; epithelial cells; palladium ... See more keywords
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Abstract B006: Identifying the molecular signature of bi-potent prostate epithelial cells through scRNA-seq

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.prca2023-b006

Abstract: Introduction: Recent studies have shown that cells undergoing oncogenic processes usurp normal developmental pathways to escape regulators of unsolicited growth. Basal to luminal differentiation in the prostate serves as another cellular process that can go… read more here.

Keywords: day; potent prostate; prostate epithelial; epithelial cells ... See more keywords
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IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

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Published in 2020 at "Oncotarget"

DOI: 10.18632/oncotarget.27650

Abstract: Localized prostate cancer (PCa) is a manageable disease but for most men with metastatic disease, it is often fatal. A western diet has been linked with PCa progression and hyperglycaemia has been associated with the… read more here.

Keywords: prostate; mesenchymal transition; hyperglycaemia induced; hyperglycaemia ... See more keywords
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Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids

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Published in 2020 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2020.571677

Abstract: Prostate cancer (PCa) is the second leading cause of cancer-related mortality and morbidity among males worldwide. Deciphering the biological mechanisms and molecular pathways involved in PCa pathogenesis and progression has been hindered by numerous technical… read more here.

Keywords: prostate; prostate epithelial; epidermal growth; growth ... See more keywords

Toll-like receptor 10 (TLR10) exhibits suppressive effects on inflammation of prostate epithelial cells

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Published in 2019 at "Asian Journal of Andrology"

DOI: 10.4103/aja.aja_100_18

Abstract: Prostate inflammation (PI) is closely related to the development and progression of chronic prostatic diseases: benign prostatic hyperplasia and prostate cancer. Toll-like receptor (TLR) 2 has been reported to be associated with inflammatory diseases, such… read more here.

Keywords: prostate; epithelial cells; tlr2 tlr10; inflammation ... See more keywords