Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30831
Abstract: Obese men are at higher risk of advanced prostate cancer and cancer‐specific mortality; however, the biology underlying this association remains unclear. This study examined gene expression profiles of prostate tissue to identify biological processes differentially… read more here.
Keywords: prostate tissue; gene expression; prostate cancer; cancer ... See more keywords
Integrating Multi‐Omics Data to Uncover Prostate Tissue DNA Methylation Biomarkers and Target Genes for Prostate Cancer Risk
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23828
Abstract: Previous studies have indicated that specific CpG sites may be linked to the risk of prostate cancer (PCa) by regulating the expression of PCa target genes. However, most existing studies aim to identify DNA methylation… read more here.
Keywords: pca; risk; target genes; prostate tissue ... See more keywords
The Correlation of Prostate Volume and Prostate-specific Antigen Levels With Positive Bacterial Prostate Tissue Cultures.
Sign Up to like & getrecommendations! Published in 2018 at "Urology"
DOI: 10.1016/j.urology.2018.02.035
Abstract: OBJECTIVE To compare prostate volume and prostate-specific antigen (PSA) levels with bacterial growth in prostate tissue cultures. MATERIALS AND METHODS Fifty male patients who underwent transurethral prostate resection were investigated prospectively. Resection chips from the… read more here.
Keywords: prostate; prostate tissue; volume; prostate volume ... See more keywords
Bioactivity and prostate tissue distribution of metformin in a preprostatectomy prostate cancer cohort
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Cancer Prevention"
DOI: 10.1097/cej.0000000000000394
Abstract: Metformin has recently been shown to have potential to reduce prostate cancer risk. We conducted a randomized, double-blind, placebo-controlled trial to determine the modulating effects of metformin on tissue and systemic biomarkers of drug activity… read more here.
Keywords: prostate tissue; metformin; prostate cancer; tissue ... See more keywords
Telocytes play a key role in prostate tissue organisation during the gland morphogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13234
Abstract: Telocytes are CD34‐positive interstitial cells, known to exert several functions, one of which is a role in tissue organisation, previously demonstrated by telocytes in the myocardium. The existence of telocytes in the prostate has recently… read more here.
Keywords: prostate tissue; telocytes play; tissue; role ... See more keywords
SAT-322 Development of Liquid Chromatography-Tandem Mass Spectrometry Method for Analysis of 11-Oxygenated Androgens in Prostate Tissue
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvaf149.2464
Abstract: Abstract Disclosure: T. Skodova: None. L. Kolatorova: None. J. Heracek: None. J. Vitku: None. Background: Androgens, along with other sex steroids, play a role in the initiation as well as the progression of prostate cancer… read more here.
Keywords: oxygenated androgens; method; none; androgens prostate ... See more keywords
Prostate and urinary microbiomes in prostate cancer development: focus on Cutibacterium acnes
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2025.1562729
Abstract: Prostate cancer (PCa) is one of the most prevalent malignancies among men, with its incidence steadily increasing worldwide. Recent advances in microbiome research have opened new avenues for understanding and treating PCa; however, studies focusing… read more here.
Keywords: cutibacterium acnes; cancer; prostate; prostate cancer ... See more keywords
Harnessing the Utility of Ex Vivo Patient Prostate Tissue Slice Cultures
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.864723
Abstract: Patient-derived prostate tissue explant cultures are powerful research tools that offer the potential for personalized medicine. These cultures preserve the local microenvironment of the surrounding stroma but are not without limitations and challenges. There are… read more here.
Keywords: tissue slice; utility; prostate tissue; tissue ... See more keywords
Prostate Tissue-Induced Platelet Activation and Platelet–Neutrophil Aggregation Following Transurethral Resection of the Prostate Surgery: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2025 at "Biomedicines"
DOI: 10.3390/biomedicines13041006
Abstract: Background: This study aimed to investigate the effects of prostate tissue on platelet activation markers, primarily assessed through P-selectin expression, and to assess the formation of platelet–leukocyte aggregations in response to prostate tissue exposure. Furthermore,… read more here.
Keywords: platelet activation; prostate tissue; aggregation; platelet ... See more keywords
Human Prostate Tissue MicroRNAs and Their Predicted Target Pathways Linked to Prostate Cancer Risk Factors
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13143537
Abstract: Simple Summary Prostate cancer is a major medical issue in men worldwide. In 2018, prostate cancer was the most frequently diagnosed cancer among men in developed countries. MicroRNAs seem to be important regulators of prostate… read more here.
Keywords: cancer; risk factors; prostate tissue; prostate cancer ... See more keywords
A Description and Safety Overview of Irreversible Electroporation for Prostate Tissue Ablation in Intermediate-Risk Prostate Cancer Patients: Preliminary Results from the PRESERVE Trial
Sign Up to like & getrecommendations! Published in 2024 at "Cancers"
DOI: 10.3390/cancers16122178
Abstract: Simple Summary The PRESERVE study is the first, large, prospective, pivotal trial of irreversible electroporation using the NanoKnife System for the prostate in the United States. The data from this United States Food and Drug… read more here.
Keywords: prostate; irreversible electroporation; intermediate risk; safety ... See more keywords