Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc.
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DOI: 10.1038/s41418-022-00960-x
Abstract: MYC drives the tumorigenesis of human cancers, including prostate cancer (PrCa), thus deubiquitinase (DUB) that maintains high level of c-Myc oncoprotein is a rational therapeutic target. Several ubiquitin-specific protease (USP) family members of DUB have… read more here.
Keywords: prostatic tumorigenesis; otud6a; prca; myc ... See more keywords