Sophocarpine attenuates wear particle‐induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF‐κB signalling pathway in a rat model
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DOI: 10.1111/bph.14092
Abstract: Aseptic prosthesis loosening, caused by wear particles, is one of the most common causes of arthroplasty failure. Extensive and over‐activated osteoclast formation and physiological functioning are regarded as the mechanism of prosthesis loosening. Therapeutic modalities… read more here.
Keywords: bone resorption; prosthesis loosening; implant loosening;
Interaction Between Staphylococcal Biofilm and Bone: How Does the Presence of Biofilm Promote Prosthesis Loosening?
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.01602
Abstract: With the aging of population, the number of indications for total joint replacement is continuously increasing. However, prosthesis loosening can happen and is related to two major mechanisms: (1) aseptic loosening due to prosthesis micromotion… read more here.
Keywords: loosening; bone; biofilm; prosthesis loosening ... See more keywords