Involvement of SNARE Protein Interaction for Non-classical Release of DAMPs/Alarmins Proteins, Prothymosin Alpha and S100A13
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-020-00950-y
Abstract: Prothymosin alpha (ProTα) is involved in multiple cellular processes. Upon serum-free stress, ProTα lacking a signal peptide sequence is non-classically released from C6 glioma cells as a complex with Ca 2+ -binding cargo protein S100A13.… read more here.
Keywords: snare; syt; serum free; s100a13 ... See more keywords
SAGE-prot: scoring-assisted generative exploration for multi-objective protein design
Sign Up to like & getrecommendations! Published in 2025 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbaf585
Abstract: Abstract Designing proteins with multiple optimized properties remains a fundamental challenge in biotechnology, especially when design objectives exhibit trade-offs or when structural templates are unavailable. We present scoring-assisted generative exploration for proteins (SAGE-Prot), a modular… read more here.
Keywords: prot; scoring assisted; language; sage prot ... See more keywords
MOCASSIN‐prot: a multi‐objective clustering approach for protein similarity networks
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx755
Abstract: Motivation Proteins often include multiple conserved domains. Various evolutionary events including duplication and loss of domains, domain shuffling, as well as sequence divergence contribute to generating complexities in protein structures, and consequently, in their functions.… read more here.
Keywords: clustering; multi objective; approach; prot ... See more keywords
Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha-Mediated CD8+ T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Circulation"
DOI: 10.1161/circulationaha.121.057301
Abstract: BACKGROUND Rheumatic heart valve disease (RHVD) is a leading cause of cardiovascular death in low- and middle-income countries and affects predominantly women. The underlying mechanisms of chronic valvular damage remain unexplored and regulators of sex… read more here.
Keywords: prot; valve disease; valve; alpha ... See more keywords
Effects of Protease Addition and Replacement of Soybean Meal by Corn Gluten Meal on the Growth of Broilers and on the Environmental Performances of a Broiler Production System in Greece
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169511
Abstract: An experimental study was conducted to examine the combined effects of adding a dietary protease, reducing the levels of soybean meal (SBM) and introducing corn gluten meal (CGM) in the ration of a group of… read more here.
Keywords: corn; control; meal; group ... See more keywords
Feeder-cell-free system for ex vivo production of natural killer cells from cord blood hematopoietic stem and progenitor cells
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1531736
Abstract: Introduction Natural Killer (NK) cells hold significant promise as therapeutic agents in immuno-oncology due to their ability to target and eliminate cancerous and infected cells without causing graft-versus-host disease or cytokine release syndrome. However, the… read more here.
Keywords: system; cord blood; prot; culture ... See more keywords
Prothymosin α Gene Transfer Modulates Myocardial Remodeling after Ischemia-Reperfusion Injury.
Sign Up to like & getrecommendations! Published in 2022 at "Acta Cardiologica Sinica"
DOI: 10.6515/acs.202203_38(2).20211115a
Abstract: Background Prothymosin α (ProT), a polypeptide, attenuates inflammation and inhibits transforming growth factor (TGF)-β signaling in pulmonary tissues. We investigated the potential role of ProT in myocardial ischemia-reperfusion (MyoIR) injury using ProT cDNA transfer. Methods… read more here.
Keywords: transfer; prot; reperfusion; gene transfer ... See more keywords