The state of the art of PROTAC technologies for drug discovery.
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DOI: 10.1016/j.ejmech.2022.114290
Abstract: Protein degradation technology has progressed dramatically since 2001 when proteolysis targeting chimera (PROTAC) was first reported. Various of distinctive degradation technologies based on PROTAC have been developed for the degradation of kinases, nuclear receptors, epigenetic… read more here.
Keywords: technologies drug; protac; protac technologies; degradation ... See more keywords