TF-PROTACs Enable Targeted Degradation of Transcription Factors.
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DOI: 10.1021/jacs.1c03852
Abstract: Transcription factors (TFs) represent a major class of therapeutic targets for the treatment of human diseases including cancer. Although the biological functions and even crystal structures of many TFs have been clearly elucidated, there is… read more here.
Keywords: degradation; protacs enable; targeted degradation; enable targeted ... See more keywords