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Published in 2021 at "Cancers"
DOI: 10.3390/cancers13215506
Abstract: Simple Summary Cyclin-dependent kinases (CDKs) are rich and viable therapeutic targets for various cancers. The emergence of event-driven pharmacology as an alternative to occupancy-driven pharmacology has begun to address the challenges associated with selectively targeting…
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Keywords:
protein;
protacs molecular;
cyclin dependent;
therapeutic modalities ... See more keywords
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Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph16010046
Abstract: Natural products are an important source of drug lead compounds, and natural products with significant biological activity are constantly being discovered and used in clinical practice. At present, natural products play an important role in…
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Keywords:
natural products;
targeted degradation;
degradation agents;
protacs molecular ... See more keywords