Articles with "protamine" as a keyword



A Pyrene-Derived Fluorescent Probe for the Visual Detection of Protamine and Trypsin Activity

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Published in 2025 at "Journal of Fluorescence"

DOI: 10.1007/s10895-024-04122-9

Abstract: A pyrene-derived fluorescent probe (P4CG) was designed and synthesized for the purpose of detecting protamine and trypsin activity. The anionic probe self-assembled with protamine, driven by electrostatic and hydrophobic interactions, exhibiting a sensing behavior towards… read more here.

Keywords: protamine; trypsin activity; trypsin; probe ... See more keywords

Quantitative determination of dextran sulfate and pentosan polysulfate and their binding with protamine using chronopotentiometry with polyion-selective electrodes.

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Published in 2021 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2021.338208

Abstract: We report for the first time a chronopotentiometric measurement of polyanions based on localized ion depletion at the sample/membrane interface at a characteristic transition time τ, using polymer membrane polyanion-selective electrodes. Chronopotentiometric transduction of polyions… read more here.

Keywords: protamine; selective electrodes; transition time; time ... See more keywords
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DNA looping by protamine follows a nonuniform spatial distribution.

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Published in 2021 at "Biophysical journal"

DOI: 10.1016/j.bpj.2021.04.022

Abstract: DNA looping plays an important role in cells in both regulating and protecting the genome. Often, studies of looping focus on looping by prokaryotic transcription factors like lac repressor or by structural maintenance of chromosomes… read more here.

Keywords: protamine; dna; looping protamine; spatial distribution ... See more keywords

Rapid and visual detection of protamine based on ionic self-assembly of a water soluble perylene diimide derivative

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Published in 2020 at "Dyes and Pigments"

DOI: 10.1016/j.dyepig.2020.108456

Abstract: Abstract In this report, a water soluble perylene diimide derivative (PDI-Glu) was designed and prepared for rapid and visual detection of protamine. The sensing performance and mechanism of this probe toward protamine was investigated systematically… read more here.

Keywords: perylene diimide; soluble perylene; detection; protamine ... See more keywords

The Association of Certain Seminal Phthalate Metabolites on Spermatozoa Apoptosis: An Exploratory Mediation Analysis via sperm protamine.

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Published in 2022 at "Environmental pollution"

DOI: 10.1016/j.envpol.2022.118969

Abstract: Earlier studies have suggested that exposure to phthalates (PAEs) may induce spermatozoa apoptosis. Sperm protamine as a molecular biomarker during spermatozoa apoptotic processes may mediate the association between PAE exposure and spermatozoa apoptosis. This study… read more here.

Keywords: spermatozoa apoptosis; sperm protamine; protamine; association ... See more keywords

Protamine use in transcarotid artery revascularization is associated with lower risk of bleeding complications without higher risk of thromboembolic events.

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Published in 2020 at "Journal of vascular surgery"

DOI: 10.1016/j.jvs.2020.02.019

Abstract: OBJECTIVE Recent studies have found that transcarotid artery revascularization (TCAR) is associated with lower risk of stroke or death compared with transfemoral carotid artery stenting but higher risk of bleeding complications, presumably associated with the… read more here.

Keywords: tcar; risk; protamine; protamine use ... See more keywords

Heparin-MPA dual modified CdS quantum dots used as a simple and rapid label-free fluorescent sensor for protamine and hemin detection

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Published in 2017 at "Microchemical Journal"

DOI: 10.1016/j.microc.2017.03.045

Abstract: Abstract Hererin, we reported a fluorescent “turn-on-off” nanosensor based on mercaptopropionic acid (MPA) and heparin (Hep) dual modified CdS quantum dots (Hep-MPA-CdS QDs), which is used for protamine and hemin detection with good sensitivity and… read more here.

Keywords: detection; protamine; protamine hemin; dual modified ... See more keywords

Quantitative determination of protamine using a fluorescent protein chromophore-based AIE probe

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Published in 2021 at "Tetrahedron"

DOI: 10.1016/j.tet.2021.132218

Abstract: Abstract An aggregation induced emission (AIE) fluorescent protein chromophore derivative CIC-FP for detecting protamine and heparin under physiological environment was designed and synthesized. CIC-FP exhibited good biocompatibility and a large stoke shift (91 nm), thus well… read more here.

Keywords: cic; protein chromophore; protamine; quantitative determination ... See more keywords

Formation of Protamine and Zn–Insulin Assembly: Exploring Biophysical Consequences

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c04419

Abstract: The insulin–protamine interaction is at the core of the mode of action in many insulin formulations (Zn + insulin + protamine) and to treat diabetes, in which protamine is added to the stable form of… read more here.

Keywords: protamine; formation protamine; insulin protamine; study ... See more keywords

A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform

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Published in 2020 at "RSC Advances"

DOI: 10.1039/d0ra03970e

Abstract: In this work, a simple melting method was developed for carbon quantum dot fabrication to integrate with protamine as an effective signal-on fluorescence strategy for trypsin detection. read more here.

Keywords: carbon quantum; protamine; quantum dot;

Clinical Impact of Protamine Titration-Based Heparin Neutralization in Patients Undergoing Coronary Bypass Grafting Surgery.

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Published in 2019 at "Journal of cardiothoracic and vascular anesthesia"

DOI: 10.1053/j.jvca.2019.01.026

Abstract: OBJECTIVES A hemostasis management system (HMS) is a point-of-care method for heparin and protamine titration. The authors hypothesized that protamine dosing over the HMS estimate would be associated with elevated activated clotting time (ACT), increased… read more here.

Keywords: bypass; protamine; estimate; ratio ... See more keywords