Quantitative determination of dextran sulfate and pentosan polysulfate and their binding with protamine using chronopotentiometry with polyion-selective electrodes.
Sign Up to like & getrecommendations! Published in 2021 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2021.338208
Abstract: We report for the first time a chronopotentiometric measurement of polyanions based on localized ion depletion at the sample/membrane interface at a characteristic transition time τ, using polymer membrane polyanion-selective electrodes. Chronopotentiometric transduction of polyions… read more here.
Keywords: protamine; selective electrodes; transition time; time ... See more keywords
DNA looping by protamine follows a nonuniform spatial distribution.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.04.022
Abstract: DNA looping plays an important role in cells in both regulating and protecting the genome. Often, studies of looping focus on looping by prokaryotic transcription factors like lac repressor or by structural maintenance of chromosomes… read more here.
Keywords: protamine; dna; looping protamine; spatial distribution ... See more keywords
Rapid and visual detection of protamine based on ionic self-assembly of a water soluble perylene diimide derivative
Sign Up to like & getrecommendations! Published in 2020 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2020.108456
Abstract: Abstract In this report, a water soluble perylene diimide derivative (PDI-Glu) was designed and prepared for rapid and visual detection of protamine. The sensing performance and mechanism of this probe toward protamine was investigated systematically… read more here.
Keywords: perylene diimide; soluble perylene; detection; protamine ... See more keywords
The Association of Certain Seminal Phthalate Metabolites on Spermatozoa Apoptosis: An Exploratory Mediation Analysis via sperm protamine.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.1016/j.envpol.2022.118969
Abstract: Earlier studies have suggested that exposure to phthalates (PAEs) may induce spermatozoa apoptosis. Sperm protamine as a molecular biomarker during spermatozoa apoptotic processes may mediate the association between PAE exposure and spermatozoa apoptosis. This study… read more here.
Keywords: spermatozoa apoptosis; sperm protamine; protamine; association ... See more keywords
Protamine use in transcarotid artery revascularization is associated with lower risk of bleeding complications without higher risk of thromboembolic events.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of vascular surgery"
DOI: 10.1016/j.jvs.2020.02.019
Abstract: OBJECTIVE Recent studies have found that transcarotid artery revascularization (TCAR) is associated with lower risk of stroke or death compared with transfemoral carotid artery stenting but higher risk of bleeding complications, presumably associated with the… read more here.
Keywords: tcar; risk; protamine; protamine use ... See more keywords
Heparin-MPA dual modified CdS quantum dots used as a simple and rapid label-free fluorescent sensor for protamine and hemin detection
Sign Up to like & getrecommendations! Published in 2017 at "Microchemical Journal"
DOI: 10.1016/j.microc.2017.03.045
Abstract: Abstract Hererin, we reported a fluorescent “turn-on-off” nanosensor based on mercaptopropionic acid (MPA) and heparin (Hep) dual modified CdS quantum dots (Hep-MPA-CdS QDs), which is used for protamine and hemin detection with good sensitivity and… read more here.
Keywords: detection; protamine; protamine hemin; dual modified ... See more keywords
Quantitative determination of protamine using a fluorescent protein chromophore-based AIE probe
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132218
Abstract: Abstract An aggregation induced emission (AIE) fluorescent protein chromophore derivative CIC-FP for detecting protamine and heparin under physiological environment was designed and synthesized. CIC-FP exhibited good biocompatibility and a large stoke shift (91 nm), thus well… read more here.
Keywords: cic; protein chromophore; protamine; quantitative determination ... See more keywords
Formation of Protamine and Zn–Insulin Assembly: Exploring Biophysical Consequences
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04419
Abstract: The insulin–protamine interaction is at the core of the mode of action in many insulin formulations (Zn + insulin + protamine) and to treat diabetes, in which protamine is added to the stable form of… read more here.
Keywords: protamine; formation protamine; insulin protamine; study ... See more keywords
A simple fluorescence assay for trypsin through a protamine-induced carbon quantum dot-quenching aggregation platform
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra03970e
Abstract: In this work, a simple melting method was developed for carbon quantum dot fabrication to integrate with protamine as an effective signal-on fluorescence strategy for trypsin detection. read more here.
Keywords: carbon quantum; protamine; quantum dot;
Clinical Impact of Protamine Titration-Based Heparin Neutralization in Patients Undergoing Coronary Bypass Grafting Surgery.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2019.01.026
Abstract: OBJECTIVES A hemostasis management system (HMS) is a point-of-care method for heparin and protamine titration. The authors hypothesized that protamine dosing over the HMS estimate would be associated with elevated activated clotting time (ACT), increased… read more here.
Keywords: bypass; protamine; estimate; ratio ... See more keywords
Modified dextran, heparin-based triggered release microspheres for cardiovascular delivery of therapeutic drugs using protamine as a stimulus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2017.1323036
Abstract: Abstract In this study, we describe the synthesis of an amine-modified acetalated dextran polymer, which is combined with heparin (HP) as the basis for a novel controlled release system. Dextran-amine (DEXAM) conjugates, synthesised using reductive… read more here.
Keywords: release microspheres; protamine; delivery; dextran ... See more keywords