Programmable biomolecular switches for rewiring flux in Escherichia coli
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-11793-7
Abstract: Synthetic biology aims to develop programmable tools to perform complex functions such as redistributing metabolic flux in industrial microorganisms. However, development of protein-level circuits is limited by availability of designable, orthogonal, and composable tools. Here,… read more here.
Keywords: switches rewiring; flux; rewiring flux; biomolecular switches ... See more keywords
On the cutting edge: protease-based methods for sensing and controlling cell biology
Sign Up to like & getrecommendations! Published in 2020 at "Nature Methods"
DOI: 10.1038/s41592-020-0891-z
Abstract: Sequence-specific proteases have proven to be versatile building blocks for tools that report or control cellular function. Reporting methods link protease activity to biochemical signals, whereas control methods rely on engineering proteases to respond to… read more here.
Keywords: cell biology; biology; based methods; protease based ... See more keywords
Construction of Mitochondrial Protection and Monitoring Model of Lon Protease Based on Machine Learning under Myocardial Ischemia Environment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Environmental and Public Health"
DOI: 10.1155/2022/4805009
Abstract: The localization of a protein's submitochondrial structure is important for therapeutic design of associated disorders caused by mitochondrial abnormalities because many human diseases are directly tied to mitochondria. When Lon protease expression changes, glycolysis replaces… read more here.
Keywords: mitochondrial protection; protease based; lon protease; model lon ... See more keywords