Dissecting the Side Chain Interaction Energies of the Active Site Hydrogen Bond Network in a Rhomboid Protease GlpG
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.507
Abstract: The intramembrane rhomboid proteases are of particular interest due to their ability to hydrolyze a substrate peptide bond at the active site which is buried within the membrane. The high-resolution structure of the E. coli… read more here.
Keywords: rhomboid protease; protease glpg; bond; active site ... See more keywords
Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-51989-0
Abstract: Polymers can facilitate detergent-free extraction of membrane proteins into nanodiscs (e.g., SMALPs, DIBMALPs), incorporating both integral membrane proteins as well as co-extracted native membrane lipids. Lipid-only SMALPs and DIBMALPs have been shown to possess a… read more here.
Keywords: polymer nanoparticles; rhomboid protease; protease glpg; lipid polymer ... See more keywords