Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra04876c
Abstract: On Wednesday 11th March, 2020, the world health organization (WHO) announced novel coronavirus (COVID-19, also called SARS-CoV-2) as a pandemic. read more here.
Keywords: anti inflammatory; antiallergic covid; inflammatory antiallergic; covid protease ... See more keywords
N-glycosylation on Asn-57 is required for the correct HAI-2 protein folding and protease inhibitory activity.
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DOI: 10.1093/glycob/cwad002
Abstract: Hepatocyte growth factor activator inhibitor (HAI)-2, is an integral membrane Kunitz-type serine protease inhibitor that regulates the proteolysis of matriptase and prostasin in a cell-type selective manner. The cell-type selective nature of HAI-2 function depends… read more here.
Keywords: glycosylation asn; hai; protease inhibitory; type ... See more keywords
Synthesis and SARS-CoV-2 3CL Protease Inhibitory Effects of Oxazolidinone Derivatives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Brazilian Chemical Society"
DOI: 10.21577/0103-5053.20220033
Abstract: The 3-chymotrypsin-like protease (3CLpro) is an attractive target for the development of anti- SARS (severe acute respiratory syndrome) drugs. In this work, a series of oxazolidinone derivatives 3a-3v were synthesized and their inhibitory activities against… read more here.
Keywords: protease inhibitory; sars cov; synthesis sars; 3cl protease ... See more keywords