Intramembrane protease RHBDL4 cleaves oligosaccharyltransferase subunits to target them for ER-associated degradation
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DOI: 10.1242/jcs.243790
Abstract: ABSTRACT The endoplasmic reticulum (ER)-resident intramembrane rhomboid protease RHBDL4 generates metastable protein fragments and together with the ER-associated degradation (ERAD) machinery provides a clearance mechanism for aberrant and surplus proteins. However, the endogenous substrate spectrum… read more here.
Keywords: rhbdl4; protease rhbdl4; associated degradation; intramembrane ... See more keywords