Improving the alkaline stability of pepsin through rational protein design using renin, an alkaline-stable aspartic protease, as a structural and functional reference.
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DOI: 10.1016/j.enzmictec.2021.109871
Abstract: The present study sought to identify the structural determinants of aspartic protease structural stability and activity at elevated pH. Various hypotheses have been published regarding the features responsible for the unusual alkaline structural stability of… read more here.
Keywords: protease structural; alkaline stability; stability; aspartic protease ... See more keywords