HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts
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DOI: 10.1155/2020/9369524
Abstract: Aging has been characterized with the accumulation of oxidized proteins, as a consequence of progressive decline in proteostasis capacity. Among others, proteasomal system is an efficient protein turnover complex to avoid aggregation of oxidized proteins.… read more here.
Keywords: mild hyperthermia; hsp70; proteasomal system; hyperthermia conditions ... See more keywords