Proteasome-associated HECT-type ubiquitin ligase activity is required for plant immunity
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007447
Abstract: Regulated degradation of proteins by the 26S proteasome plays important roles in maintenance and signalling in eukaryotic cells. Proteins are marked for degradation by the action of E3 ligases that site-specifically modify their substrates by… read more here.
Keywords: proteasome associated; immunity; proteasome; ubiquitin ligase ... See more keywords
Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22126213
Abstract: The 26S proteasome is the principal protease for regulated intracellular proteolysis. This multi-subunit complex is also pivotal for clearance of harmful proteins that are produced throughout the lifetime of eukaryotes. Recent structural and kinetic studies… read more here.
Keywords: proteasome associated; proteasome; small molecule; targeting proteasome ... See more keywords