An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?
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DOI: 10.3389/fimmu.2017.01441
Abstract: Efficient and safe induction of CD8+ T cell responses is a desired characteristic of vaccines against intracellular pathogens. To achieve this, a new generation of safe vaccines is being developed accommodating single, dominant antigens of… read more here.
Keywords: cd8 cell; proteasome catalyzed; generation; peptide splicing ... See more keywords