Depleting the 19S proteasome regulatory PSMD1 subunit as a cancer therapy strategy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5775
Abstract: Proteasome inhibitors are in use in treating certain types of cancers. These drugs inhibit the catalytic activity of the 20S proteasome, shared by all the different proteasome complexes. Inhibitors of the 26S‐associated deubiquitinating activity explicitly… read more here.
Keywords: proteasome regulatory; depleting 19s; 19s proteasome; strategy ... See more keywords
De Novo Disruption of the Proteasome Regulatory Subunit PSMD12 Causes a Syndromic Neurodevelopmental Disorder.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2017.03.003
Abstract: HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad,… read more here.
Keywords: novo disruption; disruption proteasome; subunit psmd12; proteasome regulatory ... See more keywords