Activating Adenosine Monophosphate–Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
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DOI: 10.1002/hep.31568
Abstract: Fibroblast growth factor (FGF) 1 demonstrated protection against nonalcoholic fatty liver disease (NAFLD) in type 2 diabetic and obese mice by an uncertain mechanism. This study investigated the therapeutic activity and mechanism of a nonmitogenic… read more here.
Keywords: fatty liver; protection nonalcoholic; fibroblast growth; growth factor ... See more keywords
TRIM31 confers protection against nonalcoholic steatohepatitis by deactivating MAP3K7.
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DOI: 10.1002/hep.32526
Abstract: BACKGROUND AND AIMS As a global health threat, nonalcoholic steatohepatitis (NASH) has been confirmed to be a chronic progressive liver disease that is strongly associated with obesity. However, no approved drugs or efficient therapeutic strategies… read more here.
Keywords: nonalcoholic steatohepatitis; trim31 confers; protection nonalcoholic; confers protection ... See more keywords